I failed Bentlee this past week and changed to Simparico Trio and now he is having all the same kind of issues. The simparica pushed his body into an Addison's Crisis - his body was literally shutting down. How is your dog doing? The only thought in my head was to get home and give it to my puppy who has had few fleas, but many itching problems. My vet seems skeptical that this is related to simparica but it seems clear to me, although I realize that anecdotal cases don't prove it. I removed it immediately She just tested positive for Lyme's. I won't sleep until we all get the justice for our babies that don't have voices of their own. So we went home with her on steroids and more antibiotics and denamrin for liver. And for those who have lost their fur babies I am so sorry for your lost. It's now March 23, he still has falls but not like at first. The revolutionary chewable tablet - Simparica is highly effective in eliminating fleas and various types of ticks. I gave this for the first time to my hound and about 3 hours later, she was very unsteady on her feet, eyes half shut and then had 4 episodes of breathing rapidly that each lasted 30 seconds or so and all happened within a 30 minute period. These are the side effects that were observed: Most common is vomitting Weakness and lethargy Soft stools Loss of appetite She went 11 days with no seizures and then had another gran mal. I notified my vet and Zoetis, the company that makes this drug. Currently, for Simparica, less than 0.01% of dogs taking this medication have experienced any neurologic side effects. Its Sunday night and still vomiting. I hope I have found the culprit to his digression. These include vomiting, diarrhea, lethargy, inappetence, itching, and, very . Please advise! Different vet. He said it would take care of ticks and Trifexis doesn't. I paid $120 for 6 months of poison. You keep your dog cages? I've read that simparica takes 35 days to get out of their system. (147 Reviews) $18.38 - $44.91. Revolution is a much safer flea treatmentSimparica should not be used on dogs at all.PERIOD !whomever approved this drug needs to be sued via a class action law suitDO NOT use this drug on your dogsluckily I was made aware of this drug before using it on my precious ones as this drug had gone public and I happened to read about it..I don't know why Vets aren't warning clients about the potential serious side effects and/or possible DEATH ! Simparica Trio is the brand name of a chewable tablet that protects dogs from heartworm disease, fleas, five species of ticks, and two types of intestinal parasites. A few months back he started with a morning vomiting always on his empty tummy. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. It works by creating uncontrolled neuromuscular activity leading to death in fleas as well as some ticks and mites. I'm using milk thistle and broccoli sprout powder, and going forward I'm going to use HWF Clean Heart for heartworm prevention. Did the tremors ever stop? Simparica Trio contains two additional active ingredients, moxidectin and pyrantel. I hope it is better. I've spoken to emergency vets and they say they are booked solid and that I need to just monitor her through the night. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). If she had just taken it they could give her Charcoal. As of today, Sadie's ability to eventually meet the strict certification requirements in that pursuit, remains guarded, although her progress prior to this event had been stellar. I have an 8 year old Labrador. I thought maybe it was just a allergy break out which she's never had this long now I'm wondering if she's continuing to have a reaction. But unfortunately it's only a dog is the big Pharma tune. Advised I could call Simparica for reimbursement or to report side effects. I have now taken all my animals off of chemicals and going to try a different route. Youre an idiot then! Im so terribly sorry about your puppy. RELATED: Signs Your Dog Might Be Having a Seizure. Seizures continue and its Monday. He had gone to a new groomer and when he came home he had a seizure. DO NOT give this poison to your pets. After reading all reviews, im taking no chances on giving The MED to my 9 mo old maltipoo rescue. At the same time, it opens glutamate-gated channels, which adds to the flood of nerve communications. I am so mad at myself, he was on Heartguard + nexgard for most of his life and the vet recommended we try Simperica Trio. From classic to celeb-inspired and funny to food-based, this list of cute cat names is sure to inspire your naming adventures. Today really soft stool (not diarrhea but close). I let him back in the bedroom yesterday all went well, then this morning I woke to him peeing in the floor again. Im a new pet owner and this will sound ignorant Im sure but I had NO IDEA this is how flea meds works and completely trusted my vet who knows my dogs past sensitive history and I was given the drug not even in its package so I could read anything about it but in individual pills. Vet said they dont think it has anything to do with the Simparica. The following morning he had another small seizure. How is Simparica Trio Chewable Tablets for Dogs sold? I had placed an order with Pet Meds for the prescription before I saw any of these side effects.I will be returning this medication and order Heartgard and not sure what we will do for flea and ticks, since he turns his nos Simparica Trio, e to the Nexgard and we really dont feel safe with our Grandson around the topical or collarAny suggestions? Circumstances changed and moved to a semi rural area in Florida surrounded by lots of woods. She seems more anxious now and really attached to hubby. I feel like it was a massive overdose. Vet says not to go back to Any brand oral flea/tick meds, so well be using Frontline drops on her shoulders from now on. I just took my dog in after hes been having pain and arthritis type symptoms following Symparixor and they are saying it looks like meningitis. Saturday he started up the drinking again and threw up his breakfast. The vet and company are in consultation. It's unique because it kills more types of parasites than any other combination product available to date. She passed away soon after taking this medication. Banfield Hospital pushed" Simparica Trio" on our 16 year old Toy Poodle which caused a neurological disorder of sundowner to the point of him having two days straight of constant seizures, repetitive pacing and extreme agitation. Vet prescribed this for my 12 week old border collie Lab mix. I will update once we have results from diagnostics. We will have blood work and results this evening. The flea components vary but having had one seizure you're now prone to being sensitive to even the "safer" ones. Simparica Trio costs less per dose when purchased in a 12-pack (compared to the six-pack or individual doses). Our 3 mo.old Boston Terrier, 10 lbs, had her first dose of Simparaco yesterday. She was shaking like she was freezing. for flea and ticks? I have already had a bad experience with "k9 advantix", so I refuse to buy over the counter drugs for my 13 week old Auggie. Please do NOT use it!! I will never give him this drug again. He took simparica trio 3 weeks ago and I cant wait until its out of his system! I thought maybe he got into something. I gave my morkie poo simparica trio from age 4 months until age 1 on advice of his vet. We have spent well over $5000.00 and upset about all the horror stories we are now hearing. Never again are my dogs getting oral medication for fleas & ticks. Wow. That was when I lived in Fort Lauderdale. I hate pills for me so I struggle giving this to him. She looked it up and said they were a ton of recalls and she admitted to me that that is what possibly killed him because it was on the recalls and theyd had mini dogs come in for the same issue. So new pup goes on garlic tabs-as he growing I'm upping the amount because I wanted him to be protected. This is an eye opener for me! I will not give it to my puppy again, but what is a safer med. Furious that this out there for pets. Simparica is available in different doses for dogs 2.8 pounds and over, but has not been evaluated for use in pregnant, breeding or nursing pets. Sunday, he was lethargic and refused to eat. He was a dog you could pick up anytime and he was good as gold. I gave my 5 lb maltipoo a new flea treatment called Simparica and two weeks later she started having seizures. Anyone else have the same eye issues? He had no medical problems before this, and I took him to the vet every year he ended up dying two weeks later , I took him to the vet first they told me he wasnt gonna make it to leave him there and I told him no if he isnt gonna make it, hes going to pass away in my arms at home with me and his family why took him to a different vet not the same one I confronted the woman that gave me that medicine. Then we seen an ad on tv for Simparica and it mentioned seizures as a side effect. He has no appetite and very little drinking either so hes not using the bathroom much. Today March 20 (8 week old) I get a message saying the puppy ate one of these pills that was for the bigger dog she already owned. He had his second dose on 3rd July. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. The FDA is alerting pet owners and veterinarians of the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class. Zoetis claims it will be out of his system in two months and I should not see lasting effects, so I am hopeful but worried and telling everyone I know NOT to use this poison. Would appreciate any opinion you all may have. I wish every one the best. Vet said if she vomits bring her in. I am trying to remain confident that my poor girl will recover. If there are enough reports they may have to pull it off the market until further safety tests can be done. He protected our livestock from coyotes for many years and I took good care of him. Has anyone experienced cardiac issues while under anesthesia on this medication? The most common side effects of Simparica in dogs are vomiting and diarrhea. I want to cry I wish I could get it out of her system after reading these comments. Oh how I wish I had know the side effects of this medicine I would never haven given it to her.. the company that makes this poison should be sued. I know Dukes problems were from this medicine, and it upsets me that my vet told me that this medicine was safe! I check this thread regularly and Im sooo grateful to all who wrote. I came across this site and read so much about symptoms that I now realize he has been having. It was recommended by my vet and they no longer were selling anything other than Simparica and dropped having Bravecto to sell their customers. We may also give additional medications to keep fleas, ticks, and common intestinal parasites away. Gave our Bloodhound Simparico Trip on Tuesday on Thursday he got extremely thirsty and was peeing everywhere from drinking so much water. He is not the same puppy prior to two days ago! But im 99% sure the simparica is what caused it. The costs associated with these two products are roughly the same. Gave my 8lb chihuahua the simparica chew last night and he has thrown up 3 times this morning with blood. (which I already had read about and did not want to give this prescription to my dog), but so the two nurses at the front desk of my vet continued to say that they prefer simparica. And how long for this sheet to get out of the dogs system??? In a well-controlled laboratory study, SIMPARICA TRIO began to kill fleas at 4 hours and demonstrated 100% effectiveness at 8 hours after initial administration. Nexgard can cause lethargy and a loss of appetite in dogs. They kindly asked that we schedule an immediate check and diagnostic testing at our local vet. I thought the first one it happened to may have gotten something in her eye but then a few days later the other had the same issue. I hope these steps will prevent anyone else's pet having to endure this. I am sorry you are going through this! They were taking Simperica for flea/tick and Heartguard to prevent heart worms. I gave my dog simparica trio. Very common in: Dogs of any age, breed, or gender can experience vomiting. Compared to other products, the efficiency of this . Sadly and heartbroken I report a follow up that our healthy very active 7 yr old blue tick beagle did not make it - Frazier took his last breath on February 25 2021 - he only declined the seizures continued he was fatigued all the time started losing control of his bladder - and losing his balance and walking in circles we kept hoping that once the poison was out of him he would improve but sadly he only declined I spent many nites sitting with him because the seizures were getting so bad - we tried everything but our vet tried with us but on Feb 25th our vet said that Frazier had enough and he would not recover - I did contact the company as my vet recommended and the worst customer service reps especially in this situation all they wanted was his vet records in a very matter of fact tone as I kindly replied in southern style - kiss my biscuits!! My dog weighs 60 pounds and was given a dose for dogs up to 88 pounds. The representative for the company says the half life is 16 days. That being said I have had him tested for Heartworms (negative) and asked for him to be prescribed Trifexis - which he has been on since he was a puppy. Hoping that these side effects dont get worse and subside soon . My Labradoodle had extreme diarrhea last night. Today she has fallen 2 or 3 times in the last 8 hours). Got a new GS when the old one died. My dog was HEALTHY and HAPPY prior to giving him this drug and literally days later he is struggling to recover. I realized it was from the simparica. only 7 yrs old and I still considered a puppy b/c of how active he was, we are on 8 days now of the lethargic not eating, goopy eyes - Dr says he has hyernaited disc but I have yet to see the xrays to confirm - blood work came back normail. I am worried! Those jaw spasms have decreased but were pretty alarming in Dec and January. Coton de Tulear. Haven't noticed any other symptoms to him besides the puking, not eating and skittish. I am feeding her foods such as spirulina; b12 and a special healing earth in her dinner. I will have to keep an eye out on her. Anything with tick prevention is in the same class of drugs. He is sometimes picky with his food, so I mixed in some green beans, etc but he stopped eating anything and had bright orange diarrhea by the 31st. Can my dog still get Lyme disease from a tick that was in him. I hope it is taken off the market and request that anyone on this thread with a pet who has suffered due to this drug goes to this link from the FDA to officially report their pet's adverse side effects: https://www.fda.gov/animal-veterinary/report-problem/how-report-animal-drug-side-effects-and-product-problems. It's not worth the risk of additional seizures or other neurological effects, and it seems that his stumbling and getting tired sooner on walks are likely related. I suppose with any drug, during trials, there will be some who have side effects ranging from negligible to life threatening. I just almost had a similar incident with my 16wk cavapoo. Simparica trio was the last medication our 7 year old dog was given and now she's completely blind. Your vet should be able to answer any questions related to side effects, precautions, or special care for your dog. The doctor did blood work and gave him steroids and said to watch him carefully for the next few days. Read package insert - yes was tested on female dogs who were bred. It is Now 3 pm and Lily is on her way to the animal hospital and most likely going to have to spend the night, we will flush her with iv and hope It helps Flush It out Of her system. Weighing your dog regularly will ensure that you are using the correct product size. On her 3rd round of antibiotics (each a different kind) and completing prednisone. Wednesday morning at 5am she awoke with bloody diarrhea and it turned into just blood. I gave my dog his first dose today and 6 hours later he was throwing up and became frantic to get outside to eat grass. Another possibility would be that the dosage was to high for her (simparica comes in three different dosages). He is 11 so I attributed his slowing down on walks to aging but now he is recently limping and at times has some trouble with jumping up on the bed. Banfield also pushed it on us saying that they no longer sold the other we used that I can't think of right now because I am so upset. We all want to protect our pets from fleas, ticks and the diseases they carry, but some treatments can come with nasty side effects. The reaction lasted less than 12 hours. Just had my 1 yr old goldendoodle to the vet because he has had 3 seizures in the last month. I know it's still in her system because I am still finding dead ticks that I miss because they are the size of a sesame seed. Does any one think this could be a reaction to Simparico Trio? And how do we get the word out to everyone? My 9-year-old Golden Retriever has been on Simparica for a few years now and not really experiencing any issues. I went home and somthing didn't feel right, but I read the leaflet and it said no known side effects. But then the first time I increased from 6mg to 12mg (again on advice of the vet) as his weight increased, the tremors got noticably worse and he started stumbling for no reason. A couple of weeks later she had lost weight from not eating. The flavored, chewable tablets were consumed . But I noticed that I had to "wake him' several times in only 2 minutes time, but he wasn't sleeping, his eyes were open and I saw them rolling in the back of his head! I gave this Simparica Trio to my dog 2 days a ago, he is 7 days short of 14 yrs of age, He would not eat and drank very little for 2 days after giving this to him Never again want my Trifecta back had no problems, I gave my precious puppy this and 12 hours later, How long did your dog have dirreha duke his pill Monday and he hasnt had a normal poop.
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